Kidney Cancer Program

Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center



James Brugarolas, M.D., Ph.D.

  • One of the largest kidney cancer programs in the world
  • Survival rates that double national benchmarks for Stage 4 patients and improved across stages
  • Development of first-in-class HIF2 inhibitor drug, going from gene discovery to FDA approval in 2021
  • One of only two programs in the U.S. developing immunotherapies with a Nobel Prize-winning immunologist
  • Largest and most innovative radiation oncology program pioneering new applications
  • One of the first to develop kidney tumor ablation programs in U.S.
  • First molecular classification – setting foundation for precision medicine approaches
  • Largest robotic kidney surgery program in North Texas
  • Founding member of the first national Kidney Cancer Clinical Trials Network
  • National research hub
  • 120+ physicians and scientists
  • 18 research tracks
  • Specialized Program of Research Excellence Award, National Cancer Institute
  • Inaugural Healthcare Innovation Award Finalist, D CEO Magazine
  • Leaders in Clinical Excellence Program Award, UT Southwestern Medical Center
  • Clinical Genetics
  • Medical Oncology
  • Pediatric Oncology
  • Pediatric Urology
  • Radiation Oncology
  • Subspecialty Pathology
  • Subspecialty¬†Radiology
  • Urology

>$120 million

UT Southwestern Medical Center

Ranked No. 1 globally for health care research by Nature Index

  • 6 Nobel Laureates
  • 26 National Academy of Sciences members
  • 20 National Academy of Medicine members
  • 14 Howard Hughes Medical Institute Investigators
Harold C. Simmons Comprehensive Cancer Center
  • One of 56 comprehensive cancer centers designated by the National Cancer Institute in the U.S. and the only one in North Texas
  • One of only 33 National Comprehensive Cancer Network centers